Research output per year
Research output per year
- 34 results
Search results
-
2024
In Silico Analysis of Triamterene as a Potential Dual Inhibitor of VEGFR-2 and c-Met Receptors
Lutimba, S., Saleem, B., Aleem, E. & Mansour, M. A., 14 Dec 2024, In: Journal of Xenobiotics. 14, 4, p. 1962-1987 26 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Obesity, Physical Activity, and Cancer Incidence in Two Geographically Distinct Populations; The Gulf Cooperation Council Countries and the United Kingdom—A Systematic Review and Meta-Analysis
Gaskell, C., Lutimba, S., Bendriss, G. & Aleem, E., Dec 2024, In: Cancers. 16, 24, 4205.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Downloads (Pure) -
2023
Identifying lifestyle factors associated to co-morbidity of obesity and psychiatric disorders, a pilot study
Gaskell, C., Sarada, P., Aleem, E. & Bendriss, G., 3 May 2023, In: Frontiers in Public Health. 11, p. 1132994 1132994.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus) -
Nanoparticle-mediated cancer cell therapy: basic science to clinical applications
Verma, J., Warsame, C., Seenivasagam, R. K., Katiyar, N. K., Aleem, E. & Goel, S., 24 Feb 2023, In: Cancer and Metastasis Reviews. 42, 3, p. 601-627 27 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile46 Citations (Scopus) -
2021
Highlights on selected growth factors and their receptors as promising anticancer drug targets
Mansour, M. A., Caputo, V. S. & Aleem, E., Nov 2021, In: International Journal of Biochemistry and Cell Biology. 140, 106087.Research output: Contribution to journal › Review article › peer-review
6 Citations (Scopus) -
2020
Exopolysaccharide-peptide complex from oyster mushroom (Pleurotus ostreatus) protects against hepatotoxicity in rats
Abdel-Monem, N. M., El-Saadani, M. A., Daba, A. S., Saleh, S. R. & Aleem, E., 1 Dec 2020, In: Biochemistry and Biophysics Reports. 24, p. 100852-100852 100852.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (Scopus) -
2018
Clinical resistance associated with a novel MAP2K1 mutation in a patient with Langerhans cell histiocytosis
Azorsa, D. O., Lee, D. W., Wai, D. H., Bista, R., Patel, A. R., Aleem, E., Henry, M. M. & Arceci, R. J., 16 May 2018, In: Pediatric Blood and Cancer. 65, 9, p. e27237-e27237 e27237.Research output: Contribution to journal › Article › peer-review
Open Access15 Citations (Scopus) -
2017
Disulfiram overcomes bortezomib and cytarabine resistance in Down-syndrome-associated acute myeloid leukemia cells
Bista, R., Lee, D. W., Pepper, O. B., Azorsa, D. O., Arceci, R. J. & Aleem, E., 1 Feb 2017, In: Journal of Experimental & Clinical Cancer Research. 36, 1, p. 1-14 14 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Citations (Scopus) -
Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage
Waraky, A., Lin, Y., Warsito, D., Haglund, F., Aleem, E., Larsson, O. & Wang, X. F., 18 Sept 2017, In: Journal of Biological Chemistry. 292, 44, p. 18227-18239 13 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Citations (Scopus) -
2016
Downregulation of IGF-1 receptor occurs after hepatic linage commitment during hepatocyte differentiation from human embryonic stem cells
Waraky, A., Aleem, E. & Larsson, O., 31 Aug 2016, In: Biochemical and Biophysical Research Communications. 478, 4, p. 1575-1581 7 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (Scopus) -
2015
Targeting cell cycle regulators in hematologic malignancies
Aleem, E. & Arceci, R. J., 9 Apr 2015, In: Frontiers in Cell and Developmental Biology. 3, APR, p. 16- 16.Research output: Contribution to journal › Review article › peer-review
Open Access108 Citations (Scopus) -
2014
Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism
Waraky, A., Akopyan, K., Parrow, V., Strömberg, T., Axelson, M., Abrahmsén, L., Lindqvist, A., Larsson, O. & Aleem, E., 1 Jan 2014, In: Oncotarget. 5, 18, p. 8379-8392 14 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Citations (Scopus) -
2013
CDK2 knockdown enhances head and neck cancer cell radiosensitivity
Soffar, A., Storch, K., Aleem, E. & Cordes, N., Jul 2013, In: International Journal of Radiation Biology. 89, 7, p. 523-531 9 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
β-glucans and their applications in cancer therapy: Focus on human studies
Aleem, E., 2013, In: Anti-Cancer Agents in Medicinal Chemistry. 13, 5, p. 709-719 11 p.Research output: Contribution to journal › Review article › peer-review
68 Citations (Scopus) -
2012
Multiple antitumor effects of picropodophyllin in colon carcinoma cell lines: Clinical implications
Feng, X., Aleem, E., Lin, Y., Axelson, M., Larsson, O. & Strömberg, T., Apr 2012, In: International Journal of Oncology. 40, 4, p. 1251-1258 8 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Citations (Scopus) -
Schizophyllan inhibits the development of mammary and hepatic carcinomas induced by 7,12 dimethylbenz(α)anthracene and decreases cell proliferation: Comparison with tamoxifen
Mansour, A., Daba, A., Baddour, N., El-Saadani, M. & Aleem, E., Sept 2012, In: Journal of Cancer Research and Clinical Oncology. 138, 9, p. 1579-1596 18 p.Research output: Contribution to journal › Article › peer-review
39 Citations (Scopus) -
Serum IGFBP-3 is a more effective predictor than IGF-1 and IGF-2 for the development of hepatocellular carcinoma in patients with chronic HCV infection
Aleem, E., Elshayeb, A., Elhabachi, N., Mansour, A. R., Gowily, A. & Hela, A., Mar 2012, In: Oncology letters. 3, 3, p. 704-712 9 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Citations (Scopus) -
2011
Expression of recombinant Streptokinase from local egyptian streptococcus sp. SalMarEg
Al Sohaimy, S., Aleem, E., Hafez, E. E., Esmail, S. S., El-Saadani, M. & Moneim, N. A., 17 Aug 2011, In: African Journal of Biotechnology. 10, 45, p. 9001-9011 11 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
The mushroom extract schizophyllan reduces cellular proliferation and induces G2/M arrest in MCF-7 human breast cancer cells
Aleem, E., 2011, In: Life Science Journal. 8, 4, p. 777-784 8 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Upregulation of the insulin receptor and type i insulin-like growth factor receptor are early events in hepatocarcinogenesis
Aleem, E., Nehrbass, D., Klimek, F., Mayer, D. & Bannasch, P., Apr 2011, In: Toxicologic Pathology. 39, 3, p. 524-543 20 p.Research output: Contribution to journal › Article › peer-review
57 Citations (Scopus) -
2009
Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53
Padmakumar, V. C., Aleem, E., Berthet, C., Hilton, M. B. & Kaldis, P., May 2009, In: Molecular and Cellular Biology. 29, 10, p. 2582-2593 12 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Citations (Scopus) -
2006
CDK2 is required by MYC to induce apoptosis
Deb-Basu, D., Aleem, E., Kaldis, P. & Felsher, D. W., 15 Jun 2006, In: Cell Cycle. 5, 12, p. 1342-1347 6 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Citations (Scopus) -
Dependence of cisplatin-induced cell death in vitro and in vivo on cyclin-dependent kinase 2
Price, P. M., Yu, F., Kaldis, P., Aleem, E., Nowak, G., Safirstein, R. L. & Megyesi, J., Sept 2006, In: Journal of the American Society of Nephrology. 17, 9, p. 2434-2442 9 p.Research output: Contribution to journal › Article › peer-review
Open Access92 Citations (Scopus) -
IL-7 promotes T cell proliferation through destabilization of p27 Kip1
Wen, Q. L., Jiang, Q., Aleem, E., Kaldis, P., Khaled, A. R. & Durum, S. K., 20 Mar 2006, In: Journal of Experimental Medicine. 203, 3, p. 573-582 10 p.Research output: Contribution to journal › Article › peer-review
Open Access77 Citations (Scopus) -
Mouse models of cell cycle regulators: New paradigms
Aleem, E. & Kaldis, P., 2006, Cell Cycle Regulation. Kaldiss, P. (ed.). p. 271-328 58 p. (Results and Problems in Cell Differentiation; vol. 42).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
22 Citations (Scopus) -
PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes
Robinson-White, A. J., Leitner, W. W., Aleem, E., Kaldis, P., Bossis, I. & Stratakis, C. A., 1 Nov 2006, In: Cancer Research. 66, 21, p. 10603-10612 10 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Citations (Scopus) -
2005
Cdc2-cyclin E complexes regulate the G1/S phase transition
Aleem, E., Kiyokawa, H. & Kaldis, P., Aug 2005, In: Nature Cell Biology. 7, 8, p. 831-836 6 p.Research output: Contribution to journal › Article › peer-review
332 Citations (Scopus) -
Cell cycle sibling rivalry: Cdc2 vs. Cdk2.
Kaldis, P. & Aleem, E., Nov 2005, In: Cell cycle (Georgetown, Tex.). 4, 11, p. 1489-1492 4 p.Research output: Contribution to journal › Review article › peer-review
57 Citations (Scopus) -
2004
Cdk2 as a master of S phase entry: Fact or fake?
Aleem, E., Berthet, C. & Kaldis, P., Jan 2004, In: Cell Cycle. 3, 1, p. 34-36 3 p.Research output: Contribution to journal › Review article › peer-review
Open Access40 Citations (Scopus) -
Protein phosphatase inhibitor-1 mRNA expression correlates with neoplastic transformation of epithelial liver cells and progression of hepatocellular carcinomas.
Aleem, E., Flohr, T., Thielmann, H. W., Bannasch, P. & Mayer, D., Apr 2004, In: International Journal of Oncology. 24, 4, p. 869-877 9 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
2003
Cdk2 Knockout Mice Are Viable
Berthet, C., Aleem, E., Coppola, V., Tessarollo, L. & Kaldis, P., Oct 2003, In: Current Biology. 13, 20, p. 1775-1785 11 p.Research output: Contribution to journal › Article › peer-review
Open Access595 Citations (Scopus) -
2001
Detection and quantification of protein phosphatase inhibitor-1 gene expression in total rat liver and isolated hepatocytes
Aleem, E. A., Flohr, T., Hunziker, A., Mayer, D., Bannasch, P. & Thielmann, H. W., 2001, In: Molecular and Cellular Biochemistry. 217, 1-2, p. 1-12 12 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
2000
Induction of leukaemia in chloramphenicol-treated toads
El-Mofty, M. M., Abdelmeguid, N. E., Sadek, I. A., Essawy, A. E. & Abdel Aleem, E. A., 2000, In: Eastern Mediterranean Health Journal. 6, 5-6, p. 1026-1034 9 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Citations (Scopus) -
1997
The use of toads (Bufo regularis) in a new biological assay for screening chemicals or drugs which induce leukaemia in man
El-Mofty, M. M., Abdel-Meguid, N. E., Sadek, I. A., Essawy, A. E. & Abdel-Aleem, E. A., 1997, In: Oncology Reports. 4, 3, p. 657-660 4 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)