Multiple Endocrine Neoplasia in Children and the Importance of Screening: Part 1

Endocrine tumours are tumours, or neoplasms, that arise from endocrine glands, or tumours that secrete hormones irrespective of the site of origin ( Sarvida & O'Dorisio, 2011 ). Most commonly in children, tumours can originate in the pituitary, thyroid and adrenal glands, and germ cell tumours, but can also include neuroendocrine tumours, which are types of tumours that have originally arisen from the neural crest. This article will explore the diagnosis and management of neuroendocrine tumours in children, predominantly by discussing inherited endocrine neoplasia syndromes, the importance of developing and implementing screening programmes and how they impact clinical care, and finally the importance of patient support groups and the role the paediatric endocrine specialist nurse plays in supporting patients and their families.