Systematic Evaluation of the Impact of Involuntary Motion in Whole Body Dynamic PET

Ander Biguri, Fotis Kotasidis, Alexander C. Whitehead, Irene Burger, Brian F. Hutton, Kris Thielemans

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

Involuntary patient motion can happen in dynamic whole body (DWB) PET due to long scanning times, which may cause inaccurate quantification of tissue parameters. To quantify the impact on Patlak parameters, we simulated dynamic data using patient-derived motion fields, systematically introducing the motion at different passes of the dynamic scan, both inter and intra-frame. Estimated parameters are compared against the ground truth. Results show that errors can be large, even for small motion. Caution is advised when quantitatively evaluating DWB-PET images, if any motion has been detected.

Original languageEnglish
Title of host publication2021 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2021 and 28th International Symposium on Room-Temperature Semiconductor Detectors, RTSD 2022
EditorsHideki Tomita, Tatsuya Nakamura
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781665421133
DOIs
Publication statusPublished - 16 Oct 2021
Externally publishedYes
Event2021 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2021 - Virtual, Yokohama, Japan
Duration: 16 Oct 202123 Oct 2021

Publication series

Name2021 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2021 and 28th International Symposium on Room-Temperature Semiconductor Detectors, RTSD 2022

Conference

Conference2021 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2021
Country/TerritoryJapan
CityVirtual, Yokohama
Period16/10/2123/10/21

Keywords

  • dynamic whole body PET
  • Patlak
  • simulation

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