Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: review of randomised controlled trials from 1997 to 2017

Toby Smith, Michael Mansfield, D Hunter, Abigail Ashford

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Objective: To assess the uptake of the OMERACT-OARSI core outcome set (COS) domains in hip and/or knee osteoarthritis (OA) trials. Methods: 382 trials of hip and/or knee OA were identified from the ClinicalTrial.gov registry from 1997 to 2017. Frequency of COS adoption was assessed by year and per 5-yearly phase. Results: COS adoption decreased from 61% between 1997-2001 to 38% between 2012-2016. Pain (95%) and physical function (86%) were most consistently adopted. Patient global assessment (48%) was the principal missing domain. Conclusion: Limited adoption of the COS Domains indicates that further consideration to improve implementation is required to improved uptake. This is a pre-copyediting, author-produced document of an article accepted for publication in The Journal of Rheumatology following peer review. The definitive publisher-authenticated version will be available online at: http://www.jrheum.org/
Original languageEnglish
JournalJournal of Rheumatology
DOIs
Publication statusPublished - 1 Mar 2019
Externally publishedYes

Keywords

  • 1107 Immunology
  • Arthritis & Rheumatology
  • Domain
  • 1103 Clinical Sciences
  • Trial Registration
  • OMERACT
  • 1117 Public Health And Health Services
  • Adoption
  • Core Outcome Set

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